銆婁腑鍦嬭棩鍏搞€嬭(gu墨)瀹�锛屾敞灏勫姂涓櫎涓昏棩澶�锛岄倓鍙牴鎿�(j霉)鍒跺倷鍙婇啱(y墨)鐧傜殑闇€瑕佹坊鍔犲叾浠栫墿璩�(zh矛)锛屼互澧炲姞娉ㄥ皠鍔戠殑鏈夋晥鎬�銆佸畨鍏ㄦ€ц垏绌�(w臎n)瀹氭€�锛岄€欓鐗╄唱(zh矛)绲�(t菕ng)绋辩偤娉ㄥ皠鍔戠殑闄勫姞鍔戙€�
 閬告搰鍝佺ó鑸囦娇鐢ㄧ殑婵冨害灏嶆(j墨)楂旂劇姣掓€�锛岃垏涓昏鐒￠厤浼嶇蹇�锛屼笉褰遍熆涓昏鐨勭檪鏁堣垏鍚噺娓畾銆傚埗鍔戞垚鍝佽鏄庢浉涓篃鎳�(y墨ng)娉ㄦ槑闄勫姞鍔戠殑涓嶅悓鐢ㄩ€�銆�
 

• 澧炲姞涓昏棩婧惰В搴︾殑闄勫姞鍔�

澧炲姞涓昏棩婧惰В搴︾殑鏂规硶鏈夛細

1. 閲囩敤娣峰悎婧跺姂鎴栭潪姘存憾鍔�銆�
2. 鍔犻吀鎴栧牽锛屼娇闆ｆ憾鎬ц棩鐗╃敓鎴愬彲婧舵€ч菇銆�
3. 鍦ㄤ富钘ョ殑鍒嗗瓙绲�(ji茅)妲�(g貌u)涓婂紩鍏ヨΚ姘村熀鍦�(tu谩n)銆�
4. 鍔犲叆澧炴憾鍔戯紝濡傚悙婧�-80銆佽喗姹佺瓑銆備絾浣跨敤鍚愭韩-80鏅�(sh铆)锛屽彲鑳戒娇鍚吀鎬х殑钘ョ墿銆佽嫰鐢查唶銆佷笁姘彅涓侀唶绛夌殑浣滅敤娓涘急锛屾噳(y墨ng)浜堟敞鎰�銆�
5. 鍔犲叆鍔╂憾鍔�銆�

甯哥敤鐨勬湁锛�

• 鍚愭韩-80 锛氬父鐢ㄧ殑澧炴憾鍔�锛屽父鐢ㄩ噺0.5%-1%.涓昏鎳�(y墨ng)鐢ㄤ簬鑲屽収(n猫i)娉ㄥ皠锛屾湁杓曞井鐨勯檷澹撹垏婧惰浣滅敤锛屾晠瑕佹厧鐢�銆�

浣嗚娉ㄦ剰锛氶灒璩�(zh矛)鎴栭厷鎬ф垚鍒�锛屾憾娑插亸閰�锛屽姞鍏ュ悙婧�-80鏈�(hu矛)鍑虹従(xi脿n)娓炬縼銆�
鍚厷鎬ф垚鍒�锛屽姞鍏ュ悙婧�-80闄嶄綆娈鸿弻鏁堟灉銆�
鍚愭韩-80婊呰弻閬庣▼涓�锛屾渻(hu矛)鍑虹従(xi脿n)娓炬縼銆�
鐢ㄦ硶锛氬厛灏囪澧炴憾钘ョ墿鑸囧悙婧�-80娣峰嫽锛屽啀婧惰В銆�

• 鑶芥眮锛氳喗閰搁鐨勯垑楣斤紝甯哥敤閲�0.5-1.0%.甯哥敤鐨勬湁鐗涜喗姹�銆佽爆鑶芥眮銆佺緤鑶芥眮绛�锛屾湁銆€闆滆唱(zh矛)锛岄渶瑕佸姞宸ヨ檿鐞�銆�

浣嗚娉ㄦ剰锛氳棩娑茬殑PH锛孭H澶т簬6.9锛屾€ц唱(zh矛)绌�(w臎n)瀹�銆侾H灏忎簬6.0锛岄檷浣庡婧舵晥鏋滐紝褰遍熆鍒跺姂鐨勬緞鏄庡害銆�

• 鐢樻补锛氭槸闉ｈ唱(zh矛)鑸囬厷鎬ф垚鍒嗚壇濂界殑婧跺姂銆傜敤閲忎竴鑸偤15%-20%.
• 鍏朵粬鍔╂憾鍔戝锛氭湁姗�(j墨)閰稿強鍏堕垑楣姐€侀叞鑳鸿垏鑳洪銆傚京(f霉)鍚堟憾鍔戠郴绲�(t菕ng)銆�

 

• 骞姪涓昏棩娣锋嚫鎴栦钩鍖栫殑闄勫姞鍔�

娣锋嚫鍔�銆佷钩鍖栧姂

1. 鍔╂嚫鍔戣垏涔冲寲鍔戞噳(y墨ng)绗﹀悎涓嬪垪璩�(zh矛)閲忚姹傦細

• 鐒℃姉鍘熸€�銆佺劇姣掓€�銆佺劇鐔卞師銆佺劇鍒烘縺鎬�銆佷笉婧惰锛�
• 鑰愮啽锛屽湪婊呰弻姊濅欢涓嬩笉澶辨晥锛�
• 鏈夐珮搴︾殑鍒嗘暎鎬у拰绌�(w臎n)瀹氭€�锛岀敤灏戦噺鍗冲彲閬�(d谩)鍒扮洰鐨�锛�
• 渚涢潨鑴堟敞灏勭敤鐨勫姪鎳稿姂銆佷钩鍖栧姂蹇呴爤鍤�(y谩n)鏍兼帶鍒跺叾绮掑緫澶у皬锛屼竴鑸噳(y墨ng)灏忎簬1nm锛屽€�(g猫)鍒ョ矑寰戜笉澶т簬5nm.

1. 甯哥敤鐨勫姪鎳稿姂锛氬悙婧�-80銆佸徃鐩�-85銆佹櫘娴佺緟灏糉锛�68锛岀晶鐢插熀绾栫董绱�銆佹捣钘婚吀閳夈€佽仛涔欑儻鍚″挴鐑烽叜銆佹槑鑶�銆佺敇闇查唶銆佸北姊ㄩ唶銆佸柈纭剛閰搁媮銆佺娌圭瓑銆�
2. 甯哥敤鐨勪钩鍖栧姂锛氬嵉纾疯剛銆佽眴纾疯剛銆佹櫘娴佺緟灏糉锛�68銆佹哀涔欑儻涓欑儻鑱氬悎鐗╃瓑銆�

 

• 闃叉涓昏棩姘у寲鐨勯檮鍔犲姂

鐩殑锛氱偤浜嗛槻姝㈡敞灏勫姂涓敱浜庝富钘ョ殑姘у寲鐢�(ch菐n)鐢熺殑涓嶇┅(w臎n)瀹氱従(xi脿n)璞°€�
闃叉涓昏棩姘у寲闄ら噰鐢ㄩ檷浣庢韩搴�锛岄伩鍏嶅厜鐓�锛岄﹨(q奴)鐩℃哀姘�锛岃(di脿o)鑷崇┅(w臎n)瀹氭€уソ鐨刾H鍊煎強鎺у埗寰噺閲戝爆闆㈠瓙绛夋帾鏂藉锛屽姞鍏ユ姉姘у姂涔熻捣閲嶈浣滅敤銆�
 

1. 甯哥敤鎶楁哀鍔戝師鐞嗗強鐢ㄩ噺锛�

鍘熺悊锛氭姉姘у姂鐐轰竴椤炴槗姘у寲鐨勯倓鍘熷姂銆�
鐒︿簽纭吀閳夛紙0.1%锝�0.2%锛夈€佷簽纭吀姘垑锛�0.1%锝�0.2%锛�銆佷簽纭吀閳夛紙0.1%锝�0.2%锛夈€佺～浠ｇ～閰搁垑锛圤.1%锛�銆佺～鑴诧紙0.05%锝�0.1%锛�銆佹姉澹炶閰革紙0.05%锝�0.2%锛夌瓑銆�

2. 甯哥敤閲戝爆绲�(lu貌)鍚堝姂鍘熺悊鍙婄敤閲忥細

鍘熺悊锛氶噾灞洟瀛愬姞閫熸煇浜涘寲瀛�(xu茅)鎴愬垎鐨勬哀鍖栧垎瑙ｏ紝灏�(d菐o)鑷村埗鍔戣畩璩�(zh矛)銆傝垏閲戝爆绲�(lu貌)鍚堝姂鐢熸垚绌�(w臎n)瀹氱殑绲�(lu貌)鍚堢墿銆�
渚濆湴閰镐簩閳夋垨渚濆湴閰搁垑閳�锛屽父鐢ㄩ噺鐐�0.01%锝�0.05%.姝ゅ锛岀挵(hu谩n)宸变簩鑳哄洓閱嬮吀閳�銆丯-缇ュ熀涔欎簩鑳轰笁閱嬮吀绛変篃鍙敤銆�

3. 椹�(q奴)闄ゆ哀姘ｇ殑鎯版€ф埃楂旓細

灏囬珮绱斿害鐨勬儼鎬ф埃楂擭2鎴朇O2閫氬叆渚涢厤娑茬殑娉ㄥ皠鐢ㄦ按鎴栧凡閰嶅ソ鐨勮棩娑蹭腑锛屼娇涔嬮＝鍜屼互椹�(q奴)鐩℃憾瑙ｇ殑姘ф埃銆傚苟鍦ㄨ棩娑茬亴鍏ュ畨鐡垮悗绔嬪嵆閫氬叆N2鎴朇O2锛屼互缃彌钘ユ恫闈笂绌洪枔鐨勬哀姘�锛岀劧鍚庡啀灏佸彛銆�
 

• 瑾�(di脿o)绡€(ji茅)pH鍊肩殑闄勫姞鍔戯細鍖呮嫭閰搞€佸牽鍜岀珐娌栧姂銆�

鐩殑锛氭笡灏戝皪姗�(j墨)楂旈€犳垚鐨勫眬閮ㄥ埡婵€锛屽鍔犺棩娑茬殑绌�(w臎n)瀹氭€у強鍔犲揩钘ユ恫鐨勫惛鏀�銆�
寰炴(j墨)楂旂殑閬╂噳(y墨ng)鎬у拰绌�(w臎n)瀹氭€ц€冩叜锛岃棩娑叉噳(y墨ng)瑾�(di脿o)鑷抽仼瀹滅殑pH鍊艰寖鍦�銆傚湪钘ョ墿绌�(w臎n)瀹氭€ц壇濂界殑鍓嶆彁涓�锛岃棩娑茬殑pH鍊兼渶濂藉湪姝ｅ父浜洪珨娑茬殑pH鍊�7.4宸﹀彸锛屾垨鍦╬H鍊�7.0锝�7.6涔嬮枔銆傚儏鏈夊皯鏁�(sh霉)鍝佺ó锛屽厑瑷眕H鍊煎湪4锝�9涔嬮枔銆�
甯哥敤瑾�(di脿o)pH鍊肩殑闄勫姞鍔戯細楣介吀銆佺～閰�銆佹灨娅為吀銆佹矮姘у寲閳夛紙閴€锛�銆佺⒊閰告矮閳�銆佺７閰告矮浜岄垑銆佺７閰镐簩姘垑绛�銆�
 

• 鎶戝埗寰敓鐗╃箒娈栫殑闄勫姞鍔�

鐐轰簡闃叉娉ㄥ皠鍔戝湪鍒堕€犲拰浣跨敤閬庣▼涓薄鏌撳井鐢熺墿锛岀壒鍒ユ槸閲囩敤浣庢韩婊呰弻銆佹烤閬庨櫎鑿屾垨鐒¤弻鎿嶄綔娉曞埗鍌欑殑娉ㄥ皠娑�锛屼互鍙婂鍔戦噺鐨勬敞灏勬恫锛屾噳(y墨ng)鍔犲叆閬╁疁鎶戣弻鍔�銆備絾鐢ㄤ簬闈滆剤鎴栬剨楂撴敞灏勭殑娉ㄥ皠娑蹭竴寰嬩笉寰楀姞鎶戣弻鍔�锛涘姂閲忚秴閬�5mL鐨勬敞灏勫姂鍔犳姂鑿屽姂鏅�(sh铆)鎳�(y墨ng)鐗瑰垾鎱庨噸銆�
鎶戣弻鍔戞噳(y墨ng)绗﹀悎涓嬪垪瑕佹眰锛�
锛坙锛夋姂鑿屾晥鑳藉彲闈�锛�
锛�2锛夊皪浜洪珨鐒℃瘨瀹�锛�
锛�3锛夎垏涓昏棩鐒￠厤浼嶇蹇�锛屼笉褰遍熆钘ユ晥鑸囪唱(zh矛)閲忔鏌ワ紱
锛�4锛夋€ц唱(zh矛)绌�(w臎n)瀹�锛屼笉鏄撳彈婧害銆乸H绛夊奖闊胯€屽奖闊挎姂鑿屾晥鏋�锛�
锛�5锛変笉鑸囨鑶犲璧峰弽鎳�(y墨ng)銆�
娉ㄥ皠鍔戜腑甯哥敤鐨勬姂鑿屽姂鍙婄敤閲忥細鑻厷锛�0.25%锝�0.5%锛�銆佺敳閰氾紙0.25%锝�0.3%锛�銆佹隘鐢查厷锛�0.05%锝�0.2%锛夈€佷笁姘彅涓侀唶锛�0.25%锝�0.5%锛�銆佺閰歌嫰姹烇紙0.001%锝�0.002%锛�銆佽嫰鐢查唶锛�1%锝�3%锛�銆佸凹娉婇噾椤烇紙0.1%宸﹀彸锛夌瓑銆�
 

• 娓涜紩鐤肩棝鐨勯檮鍔犲姂

鐐烘笡杓曟敞鍏ユ敞灏勫姂鏅�(sh铆)浜洪珨鐢�(ch菐n)鐢熺柤鐥�锛屾噳(y墨ng)閰屽姞灞€閮ㄦ鐥涘姂銆�
甯哥敤鐨勬鐥涘姂鍙婄敤閲忥細鑻敳閱囷紙1%宸﹀彸锛夈€侀菇閰告櫘榄崱鍥狅紙0.5%锝�2.0%锛�銆併€€楣介吀鍒╁鍗″洜锛�0.2%锝瀕.0%锛�銆佷笁姘彅涓侀唶锛�0.3%锝�0.5%锛夈€�
 

• 瑾�(di脿o)绡€(ji茅)婊查€忓鐨勯檮鍔犲姂

缍寔琛€婕跨殑婊查€忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛�锛屼笉鍍呮槸绱�(x矛)鑳炵敓瀛樻墍蹇呴渶锛岃€屼笖鑸囦繚鎸侀珨鍏�(n猫i)姘村垎骞宠　鏈夐棞(gu膩n)锛屾晠娉ㄥ皠鍔戠殑婊查€忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夋噳(y墨ng)鐩￠噺鑸囪婕跨浉绛�銆傚嚒鑸囪婕裤€佹窔娑插叿鏈夌浉鍚屾徊閫忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夌殑婧舵恫绋辩偤绛夋徊婧舵恫锛屼緥濡傦細0.9%姘寲閳夋憾娑插拰5%钁¤悇绯栨敞灏勬恫銆傛敞鍏ラ珮婊叉憾娑诧紝绱呯窗(x矛)鑳炲洜姘村垎婊插嚭鑰岀櫦(f膩)鐢熺窗(x矛)鑳炶悗绺�锛岀劧鑰屾(j墨)楂斿皪婊查€忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夊叿鏈変竴瀹氱殑瑾�(di脿o)绡€(ji茅)鍔熻兘锛屽彧瑕佽几鍏ラ噺涓嶅お澶�锛岄€熷害涓嶅お蹇紝涓嶈嚧鐢�(ch菐n)鐢熶笉鑹奖闊�銆�
鏁呰嚚搴婁笂闈滆剤娉ㄥ叆10%銆�50%钁¤悇绯栫瓑楂樻徊婧舵恫鏄劇瀹崇殑銆�
鍙槸澶ч噺娉ㄥ叆浣庢徊婧舵恫锛屾湁鍙兘灏�(d菐o)鑷存憾琛€鐝�(xi脿n)璞�锛屽繀闋堥伩鍏嶏紝0.45%姘寲閳夋憾娑茬櫦(f膩)鐢熸憾琛€锛�0.35%姘寲閳夋憾娑插彲瀹屽叏婧惰銆�
鑴婃鑵斿収(n猫i)娉ㄥ皠锛屽繀闋堢敤绛夋徊婧舵恫銆�
甯哥敤婊查€忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夎(di脿o)绡€(ji茅)鍔戯細钁¤悇绯�銆佹隘鍖栭垑銆佺７閰搁菇鎴栨灨娅為吀楣界瓑銆�
甯哥敤鐨勮(di脿o)绡€(ji茅)绛夋徊鐨勮▓(j矛)绠楁柟娉曟槸鍐伴粸(di菐n)闄嶄綆鏁�(sh霉)鎿�(j霉)娉曞拰姘寲閳夌瓑婊茬暥(d膩ng)閲忔硶銆�
 
锛堜竴锛夊啺榛�(di菐n)闄嶄綆鏁�(sh霉)鎿�(j霉)娉�
琛€婕垮啺榛�(di菐n)鐐�-0.52鈩�锛屼换浣曟憾娑�锛屽叾鍐伴粸(di菐n)闄嶄綆鐐�-0.52鈩�锛屽嵆鑸囪婕跨瓑婊�銆�
鐐烘柟渚胯▓(j矛)绠楋紝浠ヨ▓(j矛)绠楀紡琛ㄧず锛歐=(0.52-a)/b
寮忎腑锛學鐐洪厤缃瓑婊叉憾娑查渶鍔犵瓑婊茶(di脿o)绡€(ji茅)鍔戠殑鐧惧垎姣斿惈閲�(W/V)锛沘鐐鸿棩鐗╂憾娑茬殑鍐伴粸(di菐n)涓嬮檷搴︽暩(sh霉)锛沚鐐虹瓑婊茶(di脿o)绡€(ji茅)鍔戠殑1%婧舵恫鐨勫啺榛�(di菐n)涓嬮檷搴︽暩(sh霉)銆�
渚嬪锛氬凡鐭ヨ婕垮啺榛�(di菐n)鍊肩偤-0.52鈩冿紝1%姘寲閳夌殑鍐伴粸(di菐n)鍊肩偤-0.58鈩�锛�1%鏅鍗″洜婧舵恫鐨勫啺榛�(di菐n)鍊肩偤-0.12鈩冿紝鍓囬爯(y霉)閰嶅埗2%鐨勬櫘榄崱鍥犳憾娑�100ml锛屾噳(y墨ng)鍔犲叆锛�        锛夋隘鍖栭垑瑾�(di脿o)绡€(ji茅)绛夋徊銆�
A銆�0.24g                   B銆�0.48g                 C銆�0.68g                   D銆�0.90g
瑷�(j矛)绠楋細鎳�(y墨ng)鍔犲叆姘寲閳夌殑閲廤=锛�0.52-0.12*2锛�/0.58=0.48%锛坓/ml锛�锛屾晠鎳�(y墨ng)閬告搰B绛旀銆�
 
锛堜簩锛夋隘鍖栭垑绛夋徊鐣�(d膩ng)閲忔硶
姘寲閳夌瓑婊茬暥(d膩ng)閲忔寚1g钘ョ墿鍛堢従(xi脿n)鐨勭瓑婊叉晥鎳�(y墨ng)鐩哥暥(d膩ng)浜庢隘鍖栭垑鐨勫厠鏁�(sh霉)锛屽父鐢‥渚嗚〃绀恒€�
 鐐烘柟渚胯▓(j矛)绠�锛屼互瑷�(j矛)绠楀紡琛ㄧず娉�1锛歂aCl%=0.9%-Gl*E1-G2*E2
寮忎腑锛孏1銆丟2鐐鸿棩鐗╃殑鐧惧垎婵冨害锛汦l銆丒2鐐鸿棩鐗╃殑姘寲閳夌瓑婊茬暥(d膩ng)閲�銆�
渚嬪锛氶厤鍒跺惈1锛呮捍閰稿悗棣墭鍝佺殑绛夋徊婊寸溂娑�100ml锛岄渶鍔犳隘鍖栭垑锛�  锛夊厠锛�1锛呮捍閰稿悗棣墭鍝佹憾娑茬殑姘寲閳夌瓑婊茬暥(d膩ng)閲忕偤0.17锛�
A  0.73            B  0.438          C  0.541          D  0.17
瑷�(j矛)绠楋細鎳�(y墨ng)鍔犲叆姘寲閳夛紖锛�0.9锛咃紞1锛�×0.17锛�0.73锛� 
0.73锛�×100锛�0.73 锛屾晠鎳�(y墨ng)閬告搰A銆�
浠ヨ▓(j矛)绠楀紡琛ㄧず娉�2锛氬叾瑷�(j矛)绠楀叕寮忕偤锛歑=0.009v-EW
鍏朵腑锛孹鐐洪厤鎴恦 ml绛夋徊婧舵恫闇€瑕佸姞鍏ョ殑姘寲閳夌殑閲�锛泇鐐洪厤缃憾娑茬殑楂旂⿳锛坢l锛夛紱E鐐�1鍏嬭棩鐗╃殑姘寲閳夌瓑婊茬暥(d膩ng)閲�锛沇鐐鸿棩鐗╃殑鍏嬫暩(sh霉)銆�
 
锛堜笁锛夌瓑婊叉憾娑茶垏绛夊嫉婧舵恫
绛夋徊婧舵恫锛氭徊閫忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夎垏琛€婕挎徊閫忓锛堟懇鐖炬績搴︽徊閫忓锛屾懇鐖炬徊閫忓锛夌浉绛夌殑婧舵恫銆傛湁浜涚瓑婊叉憾娑诧紙纭奸吀銆侀菇閰搁夯榛冨牽銆侀菇閰稿彲鍗″洜銆侀菇閰镐箼鍩哄棊鍟★級涓嶈兘浣跨磪绱�(x矛)鑳炵殑楂旂⿳鍜屽舰鎱�(t脿i)淇濇寔姝ｅ父銆�